Research


There are an abundance of research opportunities available to residents at the Sepulveda campus of the VAGLAHS, Olive View Medical Center, and UCLA/NPI. The opportunities are on an elective basis and residents are encouraged to pursue research experience, either participating in ongoing research projects, or applying for grants for their own research projects.


RESEARCH IN PROGRESS  

Braslow, J. Doctor Patient Relationship in Somatic Therapies

Fitten, L.J., Halgren, E. et al. Evoked potential and cognition Enhancing Drugs in Normal Aging.

Fitten, L.J., Perryman, K. Cognitive Enhancement by Oral THA in Patients with Alzheimer's Disease: Long term Follow Up

     Fitten, J., Perryman, K., Ganzel, S., and Mervis, R.

     1. Development of treatment Strategies for Alzheimer's  

           disease: Human and Animal Neuropharmacology

     2. Quantitative EEG and EEG Topographic Studies in 

          dementia, Cognition, Evoked Potentials and Diabetes 

          Mellitus

     3. The Role of Impaired Selective Attention in Driving and 

          Alzheimer's Disease

Jackson-Triche, M. Identification of Depression and  

     Treatment Strategies in Ethnic Minorities  

Kessler, C. Evoked Potential Changes to Perception of Affect

Koek, Gertsik; Pharmacocentricity in clinical 

     psychopharmacology research

Koek, Sattin: Ictal EEG recording in ECT

Koek, Yerevanian, et al: Longitudinal study of quantitative, 

     computer-analyzed electroencephanlographic activity in 

   bipolar disorder; hemispheric asymmetry and emotion

McGuire, M. Individual Differences in CSF 5-HIAA, Serotonin   

     and Social Behavior

McGuire, Michael T., M.D. Behavioral-Physiological  

     Relationships in Vervet Monkeys

Mervis, J.R., Ganzell, S.L., Fitten, L.J., Daum, G. Comparison 

     of Carbamazepine & Trazodone in the control of 

     Aggression/Agitation in Demented, Institutionalized  

     Patients.  

Schore, A.   1. Affect Regulation and the repair of the Self

                 2. The Neurobiology of Shame in Interpersonal  

                        Development

3. One Hundred Years After Freud's Project  

       For A Scientific Psychology - Is a  

       Rapprochement between Psychoanalysis 

       & Neurobiology at hand?

Yerevanian, Kock, Fraser: Serial efficacy trials of SSRI and 

     other newer generation antidepressants

 

REPRESENTATIVE PUBLICATIONS BY OUR FACULTY INCLUDE  

     (1991-2000):

Auerbach, J.E., Oleson, T.D., Solomon, G.E., "A behavioral medicine intervention as an adjunctive treatment for HIV-related illness", Psychol. and Health, 6:325-334, 1992

Brammer, Gl, Raleigh, M., McGuire, M. "Neurotransmitters and Social Status", In Social Stratification and Socioeconomic Inequality, Ellis (ed.), Praeger, 75-91

Braslow, J. "Review of The History of Mental Symptoms by German Berrios", Journal of the History of Behavioral Sciences, 33:64-65, 1997

Braslow, J., "Mental Ills & Bodily Cures: Psychiatric Treatments in the First Half of the Twentieth Century", Berkeley: University of California Press, 1997

Braslow, J., "In the Name of Therapeutics: The Practice of Sterilization in a California State Hospital", Journal of the History of Medicine and Allied Sciences, 51:29-51, 1996

Braslow, J., "The Influence of a Biological Therapy on Doctor's Narratives and Interrogations", Bulletin of the History of Medicine, 70:577-608, 1996

Braslow, J., "Effects of Therapeutic Innovation on Perception of Disease & Doctor-Patient Relationship: History of General Paralysis of Insane & Malaria Fever Therapy, 1910-1950",  American Journal of Psychiatry, 152(5):660-665, May 1995

Braslow, J. "Punishment or Therapy: Patients, Doctors and Somatic Remedies in the Early Twentieth Century",  Psychiatric Clinics of North America, 17(3):493-513, September 1994

Brown, M., Munford, A., Munford, P., "Behavior Therapy of Psychological Distress in Patients After Myocardial Infarction or Coronary Bypass", J Cardiopulmonary Rehabilitation, 13:201-210, 1993

Brown, M., Shah, P., Brody, A., Woods, S., Yager, J. "Litigation in Residency Training Programs and Suggested Due Process Guidelines for Residents in Trouble", Academic Psychiatry, Fall, 1994

DeLeon-Jones, F. "Transmitter/Receptor Theories of Depression Norepinephrine", chapter in Clinical and Biochemical Aspects of Depression, Salley Hazard, MD(ed), Synapse, 1991

DeLeon-Jones, F., Mathisen, G., et. al. "Advising AIDS Patients who Participate in Clinical Trials", AIDS Pat, C8(1):33-34, Feb. 1994

Fairbanks, L., McGuire, M. "Parent Offspring Conflict and Corporal Punishment in Primates", Corporal Punishment of Children in Theoretical Perspective M. Strquas & M. Donnelly (eds.), New Haven, Yale university Press, in press

Fitten, L.J. "The Ethics of Conducting Research with the Older Psychiatric Patients", Ant. J. Geriatric Psychiatry, in press

Fitten, L.J., "Pharmacologic treatments of Alzheimer's disease: current status and future prospects", In L'Anne Gerontologique, J.L Albarede and P. Vellas (eds), pp47-62, Serdi, Paris, 1991 

Fitten, L., Coleman, L., Siembieda, D., Yu, M., Ganzell, S., "Assessment of Capacity to Comply with Medication Regimens in Older Patients", Journal of the American Geriatrics Society, 43:361-367, April 1995

Fitten, L.J., Ganzell, S. "Therapies in Senile Dementia", Am. J. Of Psychiatry, in press

Fitten, L.J., Ganzell, S. "Spouses Assess Patient Response in a Double Blind Trial of THA and Lecithin in Alzheimer's Disease", Am. J. Of Psychiatry, 149(4):575, 1992

Fitten, L.J., Perryman, K.M. "Insight into Illness and Functional Capacity as a Function of Demential Type", J.Neuropsych & Clin. Neurosci., submitted for publication

Fitten, L., Perryman, K., O'Neill, J., Halgren, E. "Influence of Cholinesterase Inhibitors on Cortical Slow Wave Activity in Aging Nonhuman Primate", Brief Communication. Pharmacology, Biochemistry and Behavior, 49:234-239, 1994

Fitten, L.J., Perryman, K.M., Wilkinson, C.J., Little, R.J., Burns, M.M., Pachana, N., Mervis, J.R., Malmgren, R., Sienbieda, D.W., Ganzell, S. "Alzheimer and Vascular Dementias and Driving", Journal of the American Medical Association, 273(17), May 3, 1995 

Fitten, L.J., Siembieda, D., O'Neill, J., Ortiz, F., Halgren, E., Fisher, A. "Reduction of motoric agitation and restlessness by AF102B and tacrine in the macaque", J. Neuropsychiatry and Clinical Neurosciences, (In Press)

Gan, M.P., Verma, R.C., Harker, J.O., Bennett, L.R., DeLeon-Jones, F., et. al. "Comprehensive Clinical, Neurophysiologic and Neuroimaging Evaluation of HIV-1 Infection", in preparation

Gross, H., Kling, A., Henry, G., Herndon, C., Lavertsky, H. "Local Cerebral Glucose Metabolism in Patients with Long Term Behavioral and Cognitive Deficits Following Mild Closed Head Injury", J. Of Neuropsychiatry & Clinical Neuroscience, 8:324-334, 1996

Harker, J.O., Satz, P., DeLeon-Jones, F., Verma, R.C., et.al. "Measurement of Depression and Neuropsychological Impairment in HIV-1 Infection", Neuropsychology, 9(1):110-117, 1995

Harwood, I. "Towards Optimum Group Placement from the Perspective of Self and Group Experience", Group Anal., 29(2), June 1996

Hsu, B. Kling, A., Kessler, C., Knapke, K., Diefenbach, P and Elias, J. "Gender Differences in Sexual fantasy and behavior in a College Population: A Ten Year Replication", J. Of Sex and Marital Therapv, Vol. 20, No. 2, 1994

Jeste, D.V, Fitten, L.J., et al "A Survey of Geriatric Psychiatrists in the US regarding Research", Int. J. Geriatric Psychiatry, in press

Kessler, C., Kling, A. "EEG power variation in schizophrenic subgroups: effects of emotionally salient stimuli," Biol. Psychiat., 30:335-348, 1991

Kessler, C., Kling, A. "EEG stimulus salience in schizophrenia", Social Neuroscience Abs, 17(1):664, 1991

Kling, A. and Brothers, L. "The amygdala and social behavior." In: The Amygdala, John Aggelton (ed), Wiley-Liss. New York, New York, 1992

Kling, A., Lloyd, R., Tachiki, K., Prince, H., Klimenko, V and Korneva, E. "Effects of social separation on immune function and brain neurotransmitters (by microdialysis) in Cebus monkey (C. apella).," In: Neuroimmunomodulation, New York Academy of Sciences, 257-261, 1992

Kling A., Tachiki K., Lloyd R. "Neurochemical Correlates of the Kluver-Bucy Syndrome by in vivo microdialysis in Monkey", Behav Brain Res, 56:161-170, 1993

Koek RJ, Kessler C: "Probable induction of mania by risperidone", J Clin Psychiatry, 57:174-175, 1996

Koek RJ, Lloyd RL, Sattin A: "Does oxytocin release correlate with ECT's efficacy?", Biological Psychiatry, 35:963-966, 1994

Koek RJ, Mervis JR., "Parenteral lorazepam for catatonia in psychotic depression", Am J Psychiatry, in press

Koek RJ, Yerevanian BI., "Is Lamotrigine effective for treatment-refractory mania?", Pharmacopsychiatry, 31:35, 1998

Koek RJ, Yerevanina BI, Smith JC, Tachiki KH, Kopelowicz A, Alcock J., "A longitudinal QEEG study in bipolar disorder", (Abstract), Clin EEG, 27(Suppl 1):8, 1996

Koek RJ, Yerevanian BI: Tachiki KH, Alcock J, Smith JC, Kopelowicz A., "Hemispheric asymmetry in depression and mania: A longitudinal quantitative EEG study in bipolar disorder", J Affect Disord., in press

Kopelowicz, A., "Schizophrenia", In Case Studies in Abnormal Psychiatry, Gorenstein, E.E.(ed), HarperCollins College Publishers, New York, in press

Kopelowicz, A., "Adapting social skills training for Latinos with schizophrenia", International Review of Psychiatry, 10:47-50, 1998

Kopelowicz, A., "Integrating psychotherapy and pharmacology for schizophrenia", In In Session: Psychotherapy in Practice, Feldman, LB., Feldman, S. (eds), Wiley, New York, 3(2):79-98, 1997

Kopelowicz, A., "Social skills training: The mediating role of culture", Journal of Psychopathology and Behavioral Assessment, 19:101-108, 1997

Kopelowicz, A., "And when they awaken what will they find", The Journal of the California Alliance for the Mentally Ill, 7(2):15-16, 1996

Kopelowicz, A. and Bidder, T.G., "Outcome of Schizophrenia", Hospital & Community Psychiatry, 149(3):426-7, March 1992.

Kopelowicz, A., Corrigan, P., Schade, M., Liberman, R.P., "Social skills training", In Psychosocial Functioning in Schizophrenia, Mueser, K.T., Tarrier, N. (eds), pp307-326, Allyn & Bacon, Boston, MA, 1998

Kopelowicz, A., Corrigan, P., Wallace, C., Liberman, RP., "Biopsychosocial rehabilitation", In Psychiatry, Tasman, A., Kay, J., Lieberman, JA. (eds), pp1513-1534, Philadelphia, W.B. Saunders Company, 1996

Kopelowicz, A., Liberman, R.P., "Biobehavioral treatment and rehabilitation of persons with serious mental illness", In New Directions in Behavioral Interventions: Principles, Models, and Practices, Scotti, J.R. (ed), Brookes Publishing Company, Baltimore, MD, in press

Kopelowicz, A., Liberman, R.P., "Psychological and behavioral treatments for schizophrenia", In Treatments that Work, Nathan, P.E., Gorman, J.M. (eds), pp190-211, Oxford University Press, London, 1998

Kopelowicz, A., Liberman, R.P., Mintz, J., Zarate, R., "Efficacy of social skills training for deficit versus nondeficit negative symptoms in schizophrenia", American Journal of Psychiatry, 154:424-425, 1997

Kopelowicz, A., Mangano, R., Caine, M., "Teaching the seriously mentally ill about dating, intimacy, and sexuality", In Sexuality and the Seriously Mentally Ill, Buckley, P.(ed), American Psychiatric Press, Washington, in press

Kopelowicz, A., Mangano, R., Zarate, R., Tripodis, K., "The transition from the hospital to the community for the seriously mentally ill", Medscape, in press

Kopelowicz, A., Wallace, C.J., Zarate, R., "Teaching psychiatric inpatients to re-enter the community: A brief method of improving the continuity of care", Psychiatric Service, in press

Liberman, R.P., Wallace, C.J., Blackwell, G., Kopelowicz, A., Vaccaro, J.V., Mintz, J., "Skills training vs. psychosocial occupational therapy for persons with persistent schizophrenia", American Journal of Psychiatry, 155:1087-1091, 1998

Liebermann J., Schleissner L., Tachiki KH, Kling AS "Serum Alpha Antichymotripsin Level as a Marker for Alzheimer-type Dementia", Neurobiology of Aging, 16(5):747-753, 1995

MacKain, S.J., Smith, T.E., Wallace, C.J., Kopelowicz, A., "Evaluation of a community re-entry program", International Review of Psychiatry, 10:76-83, 1998

McGuire, M. Fawzy, F., Spar, J., and Troisi, A. "Regulation-disregulation theory and Dysthymic Disorder", Depression Revisited  L., Sloman (ed.), Univ. Of Toronto Press, In press

McGuire, M., Raleigh, M., Pollack, D. "Changes in Serotonin System among Separated subordinate males in Vervet monkeys", submitted to Am. J. Of Primatology

McGuire, M., Raleigh, M., Pollack, D. "Physiological and Behavioral Consequences of Partial Separation in Vervet monkeys", submitted to Am. J. Of Primatology

McGuire, M., Raleigh, M., Pollack, D. "Personality Features in Vervet Monkeys: The Effects of Sex, Age, Social Status, and Group Composition", Am. J. Of Primatologv, 33:1-13, 1994

McGuire, M., Troisi, A., Evolutionary Psychiatry, Harvard University Press, accepted for publication

McGuire, M., Weigel, R., Troisi, A. et al, "Altruism and Mental Disorders", Ethology and Sociobiology, 15:299-321, 1995

Mervis, R. "The management of depression in the Nursing Home", In Research Issues in the Nursing Home, Rubenstein, L., Weiland, D. (eds), Sage Press, 1993 

Milby, J., Sims, M.K., Haas, N., et al, "Psychiatric Comorbidity: Prevalence in Methadone Maintenance Treatment", Am. J. Drug & Alcohol Abuse, (22)1, Jan. 1996

O'Neill, J., Fitten, L.J., Siembieda, D., Crawford, K.C., Halgren, E., Fisher, A., Refai, D. "Divided attention-enhancing effects of AF102B and THA in aging monkeys", Psychopharmacology, (pending revisions)

O'Neill, J., Fitten, L.J., Siembieda, D., Halgren, E., Kim, E., Fisher, A., Perryman, K.M. "Effects of AF102B and tacrine on delayed match to sample in monkeys", Progress in Neuropsychopharmacology and Biological Psychiatry, (In Press)

Pachana, N., Cherrier, M., Ganzell, S. "False Positive Errors on Selected Tests of Malingering",  American Journal of Forensic Psychology, 16(2):17-25, 1998

Perryman, K.M. Fitten, L.J., Mendez, M. "Effects of Normal Aging on the Performance of motor Vehicle Operational Skills", J. Geriatric Psychiatry & Neurology, (in press)

 

Raleigh, M., McGuire, M. "Environmental Constraints, Serotonin, Aggression, and Violence in Vervet monkeys", In  The Neurotransmitter Revolution Masters, R.,McGuire, M. (eds.), S. Illinois Press, 1993

 

Raleigh, M., McGuire, M., Melega, W., Cherry, S., Huang, S-C, Phelps, M. "Neural Mechanisms Supporting Successful Social Decisions in Simians",  In Neurobiology of Decision Making Damasio, A.R. et al (eds), Berlin, Springer-Verlag, 63-82, 1996

 

Rapkin, A., Pollack, D., Raleigh, M., McGuire, M. "Menstrual Cycle and Social Behavior in Vervet monkeys",  Submitted to Obstetrics and Gynecology

 

Sattin, A., Kubek, M.J., Low, W.C., Staley, C.J., Simon, J.R., "Some regional anatomical relationships of TRH to 5-HT in rat limbic forebrain", Neurochemical Research, 17:469-474, 1992

 

Schore, A. "Interdisciplinary Development research as a Source of Clinical Models",  To be published as a chapter in Perspectives on Early Development - Implications for Theory and Practice, Jason Aronson, 1997

 

Schore, A. "The Experience Dependent Maturation of a Regulatory System in the Orbitofrontal Cortex and the Origin of Development Psychopathology",  Development and Psychopathology,  8:59-87, 1996

 

Schore, A. Affect Regulation and the Origin of the Self: The Neurobiology of Emotional Development,  Lawrence Erlbaum Associates, Hillsdale, N.J. April 1994

 

Suffin, S., Kling, A., Gutierrez, N., Karan, S., Arora, D. "Quantitative EEG as Predictor of Response to Antidepressant Medication in Depressed Patients", submitted for publication

 

Ventura, J., Mintz, J., Kopelowicz, A., et al, "The impact of the Northridge earthquake on the seriously and persistently mentally ill", submitted for publication

 

Verma, R.C., Gan, M.P., Bennett, L.R., DeLeon-Jones, F., et. al., "Cerebral Perfusion Imaging as a Marker of Early HIV-1 Infection in the Brain", J. Nuc. Med., 1994